By now, pretty much everyone is dialed in to the message that sugar threatens health. No doubt, this is a powerful and motivating bit of information for people to adopt dietary strategies that limit sugar exposure. Unfortunately, because of this information, we are seeing a surge in the consumption of artificially sweetened foods and beverages.

In this video, I explore the fallacy and misconception of the health benefits related to non-caloric artificial sweeteners. I explored the research that actually demonstrates a dramatic increase in risk for weight gain as well as type 2 diabetes in those individuals who favor the consumption of these foods and beverages.

What we really haven’t understood however, has been the mechanism whereby the consumption of artificially sweetened beverages relates to increased risk for these and other health problems.

New research from Israel has identified what may likely be an important mechanism explaining this relationship. As you’ll see in the video, changes in the microbiome induced by artificial sweeteners are now front and center, in terms of playing a powerful causal role in increasing the risk for these medical issues.

Please watch the entire video as I think you’ll certainly enjoy the ending!

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  • fred tully

    these are collations, and you are making these sound like causation. Bullshit.

    You are missing the psychological drive or appetite for sweetness. The problem exists before the start of the observations. The people are getting fater are those who are getting fat and switch to “diet” drinks trying to avoid the weight gain. They become a self selecting subgroup.

  • Peppino Zappulla

    I have a question for You, Dr Perlmutter: are Ménière’s disease and Tinnitus attributable to an inflammation of the brain, as Parkinson’s and Alzheimer’s? Is there research in this direction? What about your professional experience? Thanks

  • BigAl

    Please comment on the product, Stevia, which I understand is a natural or at least sugar substitute derived from a plant

    • coolmutha berta

      Yes, please do!
      I was about to ask the same question.

      • mary

        yes, is stevia triggering a craving or supporting non-beneficial intestinal flora? say it ain’t so…

        • Summit

          I do would love to know the facts on Stevia . It almost appears as if the answer we really want to hear may have some hidden studies . Im not one for vague answers such as Dr Perlmutter is providing .

          • Jessica Lynn

            I too would like to know details. I’m brand new to this lifestyle. Stevia has been my savior. Sorry to keep probing but a specific answer would really help me out. Thanks!

      • David Perlmutter

        If someone must use a sweetener, Stevia is the one I suggest.

        • Albert

          That’s a pretty luke-warm endorsement of Stevia, right, David? Can you please expand your viewpoint? What exactly are your reservations? Frankly, I’ve always felt that the idea of “sugar from a plant” was simply too good to be true. FYI, I use organic Stevia in my daily coffee, as well as to sweeten my organic yogurt, and eat hardly any sugar, but I always add the Stevia with a bit of silent reservation. I’d certainly be willing to stop completely if there were any scientific evidence in support of any possibly harmful effects. Please give me your best judgment on this subject. Thanks.

    • Allison

      My understanding is to use only Liquid Stevia (very concentrated) because it doesn’t contain the additional powders that “make it flow” like sugar & make it easier to measure quantities for baking… These additional powders are Not good for you. You can find stevia liquid @ any health food store or order online (I tend to get Vitacost brand online). I would also like to know if stevia affects gut microbiome (clearly, everything does) but I suspect that studies haven’t yet been done or, may just be starting.

      I have been using liquid stevia for ~ 6 years, in coffee & to flavor lime water. The liquid also comes in mildly flavored natural solutions like berry, watermelon… I have not experienced weight or abdominal fat gain, but one 56 year old woman doesn’t constitute a study.

  • Mary

    I decided that I would use regular sugar rather than use any artificial sweetener.
    Our bodies do seem to recognize “sweet” even if no calories.

    • David Perlmutter

      Just keep consumption as minimal as possible.

  • Lilla

    What about xylitol and erythritol? Are they good to consume? They are also found in nature.


    I think you might be appointed for a Nobel Prize in Medicine, instead of any of those MDs that practice Ideological Medicine backing all sort of Ideas they define as Scientific Health Organizations, most often interested in non Health as his business target!

  • Frances Lilian Wellington

    Yes, I enjoyed it! Thanks David. We had a similar advert for marg. here in Australia. It went, “You ought to be congratulated!” (for choosing marg, over butter). I had an inkling these processed “foodstuffs” would eventually show up their shortcomings, simply because my own body could only tolerate small amounts of brown sugar, less white sugar, zero artificial sweeteners. I tried them on one occasion, and that was it, never again. Glad I followed my instincts on this (or my MetSy would have been full blown T2DM!) This video confirms this for me. Thank you for the info in this video. I particularly liked the graphs, showing such info to others paints a very graphic picture. Can you direct me to these graphs on your blog?

  • Darren

    So to clarify. It is best not to use sugar at all, but if one uses something then Stevia is currently the best choice?

  • JohnInTheOC

    Epigenetic Therapy; Please consider a new book on this exciting frontier.

  • RicardoRichard

    Dr Perlmutter, talking about sugars, what about stevia and xylitol? I heard that they are extremely healthy as long as we do not exaggerate. And the latter is even anti-bacterial so some dentists who are abreast of time recommend cleaning our teeth with it

    • David Perlmutter

      Stevia is the best option if someone must have a sweetener.

      • RicardoRichard

        Thanks, but I was much more interested in solving the issue of anti-bacterial characteristics of xylitol. I heard about it for the first time some 5 years ago but since then the issue has been hushed down. Nobody talks about it any more.

  • Earline Worsley1

    Informative article – I was enlightened by the insight – Does anyone know where I might get access to a fillable a form copy to work with ?